Q.1
The following feature is common to both cytotoxic T cells and NK cells (AI 2002)
Synthesize antibody
Requires antibodies for their actions
Effective against virus infected cells
Recognise antigen in association with HLA class II markers
Q.2
True about NK cell is all except..
Form 5-10 % of peripheral blood lymphocytes
Cytotoxicity is not antibody dependent or MHC restricted
They are CD16 and CD56 positive
Ability of NK cell to kill target cell is directly proportional to target cell expression of MHC class I molecule
Q.3
True about NK cell is all except..(AI 2003)
Derived from large granular lymphocytes
They comprise about 5% of periferal blood lymphocytes
They are MHC restricted cytotoxic cells
They express IgG Fc receptors
Q.4
Which of the following is not a type of NULL cell / LARGE GRANULAR LYMPHOCYTE..
NK cell
Antibody dependent cytotoxic cells
LAK cells
Langerhans cells
Q.5
Which of following interleukin act as growth factor for NK -cell
IL 1
IL 2
IL 12
IL 6
Q.6
NK cells are first line of defence against virus ladden cells and neoplastic cells but dont kill normal cells because..
The viral infection or neoplastic transformation reduces MHC I expression
The viral infection or neoplastic transformation reduces MHC II expression
The viral infection or neoplastic transformation enhances MHC I expression
The viral infection or neoplastic transformation enhances MHC II expression